Beta-Cell Preservation Throughout the Stages of Type 1 Diabetes White Paper

A Clinical and Implementation Framework from the T1D Exchange Quality Improvement Collaborative Beta Cell Preservation Working Group.

Developed with clinical leaders from the T1D Exchange Quality Improvement Collaborative and grounded in current evidence and real-world implementation experience.

Early-stage T1D care is advancing quickly — implementation takes effort and consideration.

Screening and staging approaches are expanding, and disease-modifying therapies are reshaping early-stage T1D conversations. But integrating these changes into routine practice requires coordinated workflows, referral pathways, staff training and operational readiness.

What you'll find in this white paper:

• Recommended screening framework and who/when to screen
• Staging and monitoring protocols for early-stage T1D
• Practical clinical pathways for operationalizing early detection
• Considerations for operationalizing disease modifying therapy workflows
• Quality improvement strategies, measures, and benchmarking guidance
• Tools and examples (process maps, workflow illustrations, EHR-related supports)